Cannabidiol (CBD) is one of at least 85 cannabinoids found in the cannabis plant. Although THC is more often associated with cannabis plants, CBD is the most abundant, and has none of the psychoactive properties of the THC molecule. All cannabinoids act on cannabinoid receptors that are found in our body’s endocannabinoid system.
Recent research shows a number of potential benefits for our mental and physical health associated with CBD use. Some of the common effects include but are not limited to: increased levels of relaxation, heightened alertness, improved mental clarity, reduction in physical pain and inflammation, enhanced sleep, reduced anxiety and stress, and suppressed nausea.
Hemp and marijuana are both part of the cannabis genus of plants. They can be of the same or different plant species. However, if they are of the same species, they will be different varietals. For example, hemp will generally have a higher concentration of CBD, while marijuana will have a higher concentration of THC.
The legal definition of hemp requires that the plant has no more than 0.3% THC after the plant has been cultivated and dried. If the cannabis plant has more than 0.3% THC, then it cannot meet the legal definition of hemp.
Marijuana is a non-legal term that is widely used to refer to a cannabis plant that has been bred for the psychoactive molecule ofTHC. These plants can have THC levels of up to 20%-30% of the plant’s dry weight.
Yes, hemp-derived CBD is fully federally legal. The Agricultural Act of 2018 (widely known as the2018 Farm Bill) legalized hemp and hemp-derived products, provided those products do not contain more than 0.3% THC. This means that CBD derived from hemp is no longer part of the Controlled Substances Act of 1970, which previously treated both THC and CBD as Schedule 1 drugs. CBD derived from marijuana, however, is still considered a Schedule 1 drug and is still federally illegal.
No, the 2018 Farm Bill legalized hemp and hemp extracts only. Currently, the Controlled Substances Act of 1970 treats what is socially called marijuana and THC or CBD derived from marijuana as Schedule 1 drugs and are therefore federally illegal still.
No, research has shown the hemp-derived CBD that contains less than 0.3% THC does not produce psychoactive effects.
There is active research being conducted on CBD’s effect on a wide range of conditions, including but limited to: chronic pain; insomnia; PTSD; anxiety; epilepsy;sleeplessness and dementia. Both preclinical and clinical studies have shown that CBD has strong anti-oxidant, anti-inflammatory, anti-convulsant, anti-depressant, antipsychotic, anti-tumoral, and neuroprotective qualities.
Most research has concluded that CBD is not associated with side effects, though some users have reported drowsiness, lightheadedness and “dry mouth”. The World Health Organization has concluded that CBD is not addictive, and there is no evidence of public health-related problems associated with the use of pure CBD. Even chronic use and high doses up to 1,500MG per day are reportedly well tolerated in humans. Are CBD products safe?
CBD products are incredibly safe, if properly manufactured. Consumers should ensure that CBD products are produced in federally regulated facilities that are Consumer Good Manufacturing Practices (cGMP) certified. Consumers should also check for recent certificate of analysis for products they use to show the exact amount of cannabinoids in the product and to ensure it is free of pesticides, metals and other harmful materials. We are diligent to ensure that all Full Spectrum Hemp products meet these high standards.
Whole Hemp Plant (known for producing the “entourage effect”) is a term used to describe when all the natural compound are kept in the cannabis plant, such as the cannabinoids, terpenes, and flavonoids. These compounds have been shown to work better when they are taken together. Products that are full spectrum contain CBD as well as other cannabinoids, while CBD isolate is nearly pure CBD without other cannabinoids and cannabis compounds.
CBD is a cannabinoid and cannabinoids are compounds derived from the hemp plant. They work by imitating compounds our bodies naturally produce, called endocannabinoids, that affect nerve, brain, and immune cell activity.
Cannabinoids bind to our body’s cannabinoid receptors. There are two primary cannabinoid receptors: CB1 and CB2 receptors. CB1 receptors are generally located in the central nervous system. They affect appetite, muscle control, pain, cognition, thermoregulation, and stress response. CB2 receptors are primarily found in immune cells, and at a lower density in the central nervous system. CB2 activation is associated with immune function and immune cell proliferation, inflammation, and pain.
Source: Szaflarski JP, Bebin EM, Cannabis, cannabidiol, and epilepsy–from receptors to clinical response. Epilepsy Behav. 2014;41:277-82
Endocannabinoids (cannabinoids produced naturally in the body of mammals) are not neurotransmitters. Endocannabinoids are neuromodulators – they are released on demand to alter the activity of neurotransmitters. A good example is glutamate. Glutamate is a primary, stimulatory neurotransmitter. When glutamate is present in excessive amounts, pain and cell death can occur. The release of endocannabinoids functions as a stopping mechanism for the release of glutamate. CBD can act in the same way as our own endocannabinoids.
The endocannabinoid system is the collection of cannabinoid receptors, endocannabinoids (cannabinoids produced naturally in our bodies) and enzymes involved in producing and breaking down endocannabinoids. It is an integral part of our neuro-immuno-endocrine network. This system affects many aspects of human health including mood, pain, inflammation, stress responses and immune functionality.
The two most studied endocannabinoids are anandamide and 2-AG. The two most studied cannabinoid receptors are CB1 and CB2. CB1 receptors are located mostly in the brain and CB2 receptors are located mostly throughout the immune system. A “phytocannabinoid” or plant-derived cannabinoid like CBD can activate the same receptors in the body and may have similar or stronger effects than the endocannabinoids that our bodies produce naturally.
Hemp extract is the raw extracted material produced from hemp after it undergoes the initial extraction process. The hemp extract is refined over multiple stages and then purified (during which THC may also be removed) to become a CBD product such as a CBD oil tincture.
CBD isolate, or otherwise known as “pure CBD” or “99% CBD”, is the CBD molecule separated from all of the other compounds in the hemp plant. CBD isolate usually appears as a crystalline white powder. CBD isolate is considered to be less effective therapeutically than whole plant CBD-rich oil. It is believed that the aggregation of compounds from the hemp plant produces CBD product’s healing effects through complementary action. This is known as the “entourage effect”, where mixtures of cannabinoids, hemp terpenes, and perhaps other molecules such as flavonoids and stilbenoids, have a greater positive effect than just isolated CBD compounds alone.
Sources: Spelman K. “Silver Bullet” Drugs vs. Traditional Herbal Remedies: Perspectives on Malaria. HG J Am Bot Coun 84:44-55. Russo EB. Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. Br J Pharmacol. 2011 Aug;163(7):1344-64. Shimon Ben-Shabat S, Fride E, Sheskin T,Tamiri T, Rhee MH, Vogel Z. Bisogno T,De Petrocellis LD, Di Marzo V, Mechoulam R. An entourage effect: inactive endogenous fatty acid glycerol esters enhance 2-arachidonoyl-glycerol cannabinoid activity. Euro J Pharmacol. 1998;353:23–31.
Terpenes are essential oils found in plants. There are around 200 terpenes in cannabis. They are what give cannabis its distinct aroma and flavor. Terpenes may have beneficial effects and work synergistically with cannabinoids like CBD to create the entourage effect.
Before you purchase a CBD product, you should ensure that the CBD product was produced in a federally regulated facility that is Consumer Good Manufacturing Practices (cGMP) certified. If the CBD product’s seller does not provide that information, then buyer beware. Consumers should also check that the CBD products have a recent certificate of analysis (“COA”) to show the exact amount of cannabinoids in the product and to ensure it is free of pesticides, metals and other harmful materials. Again, if the seller does not provide this information, there is likely a reason why they are not providing it. Please be wary of such sellers. Lastly, we recommend that you consult with your medical practitioner about taking CBD.
CBD’s effectiveness and the time it takes to affect your body will be dependent on a number of factors unique to you (such as your weight, age, etc).
Generally speaking, however, nanoized water-soluble CBD has the fastest affect on the body. What is known as “bioavailability”, Full Spectrum Hemp’s nanoized water-soluble products take effect approximately 5x faster than non-nanoized water-soluble CBD products.
Regular CBD products that lack nanoized water-soluble CBD will take longer to be absorbed into the body’s bloodstream and therefore to take effect. However, these products generally effect the body depending on how CBD is consumed:
CBD bioavailability generally refers to how quickly the CBD enters your bloodstream and is made available to your body’s circulation system. The higher the bioavailability, the faster the CBD will take effect in your body and, likely, the stronger effect on your body.
Though CBD contains a minuscule amount of THC, as mandated by federal law, some drug tests, depending on the equipment being used, may pick up the small amount of THC in CBD products.
No. It can be helpful for addressing pain, stress, and promoting general wellness, but we do not market our products as cures for medical ailments. If a CBD product claims to cure a medical condition, please be wary about purchasing those types of products.
The amount of CBD that you should take depends on multiple factors, such as the type of CBD you are consuming, your age, weight, gender, medical history, personal preferences, etc. Please note that water-soluble CBD has higher bioavailability and will likely have a stronger impact than non-nanoized water-soluble CBD. Though this is not guidance specifically for you, we have seen many consumers take as little as 5mg of CBD and up to 150mg of CBD per day. We would recommend you consult your doctor regarding CBD dosage questions.
There is a small but growing body of research of CBD usage for pets. Pets may benefit from CBD for managing pain, inflammation, anxiety, stress, etc. If CBD is given to a pet, please consider the likely difference in weight between you and your pet, and provide a much smaller amount of CBD to your pet than what you may be taking. Also, please note that dogs have a higher concentration of cannabinoid receptors in their bodies, which means that they will likely be more sensitive to CBD and other cannabinoids than humans. We recommend that you speak with your veterinarian before you start giving your pet CBD.
At Full Spectrum Hemp, our focus is creating natural products for healthy lifestyles. What sets us apart from other CBD companies is our foundation in science and cutting edge formulations from our in-house research and development team.